Drugs with good curing effect for duodenitis include anti-Helicobacter pylori drugs, antacid drugs, acid-suppressing drugs, gastric power-promoting drugs, and mucosal protectants. 1. Anti-Helicobacter pylori drugs: often use quadruple therapy, such as omeprazole, bismuth potassium citrate, amoxicillin, clarithromycin and so on. 2. Antacid drugs: commonly used drugs include aluminum hydroxide, sodium bicarbonate, etc. 3. Acid-suppressing drugs: commonly used drugs include esomeprazole enteric-coated capsules, cimetidine tablets and so on. 4. Gastric stimulants: commonly used drugs include mosapride dispersible tablets, cisapride, domperidone and so on. 5. Mucosal protective agents: commonly used drugs are aluminum sulfate, colloidal bismuth pectin capsules. Drugs need to be used under the guidance of a doctor.