The ability to recover from diffuse axonal injury is primarily related to the severity of the initial condition. Patients with severe disease usually do not recover fully. Diffuse axonal injury is a rotational force on the head, caused by shear stress, which is mainly characterized by swelling and breakage of the neural axons in the central region of the skull. Among them, concussion belongs to a kind of light diffuse axonal injury, and most of the diffuse axonal injuries are more serious, accounting for 28% to 50% of the heavy craniocerebral injuries, which are difficult to treat and have a poor prognosis. If the concussion is a mild diffuse axonal injury, usually after rest, symptomatic treatment, about 2 weeks can be self-healing. Severe diffuse axonal injuries are usually characterized by prolonged and severe impairment of consciousness that occurs immediately after the injury. In particularly severe cases, death occurs within a few hours, and even if the patient survives, he or she is usually in a coma or vegetative state. There is no specific treatment in this case, mainly for symptomatic maintenance treatment, with a high mortality and disability rate, and very difficult to recover. When diffuse axonal injury occurs, it is recommended to seek timely medical treatment and actively cooperate with doctors to obtain maximum recovery.