Drugs for the treatment of H. pylori include a proton pump inhibitor, two antibiotics and a bismuth agent, of which the proton pump inhibitor and bismuth agent can be taken before meals and the antibiotics should be taken after meals.
The main effect of proton pump inhibitors (omeprazole, lansoprazole, pantoprazole, etc.) is to inhibit the secretion of gastric acid, thus protecting the gastric mucosa. Bismuth agents (colloidal bismuth pectin, bismuth potassium citrate, etc.) are able to protect the gastric mucosa by, among other things, reducing pepsin. Therefore these two types of drugs need to be taken before meals for better therapeutic effects.
Antibiotic drugs (Amoxicillin, Clarithromycin, etc.) can irritate the gastric mucosa, and entering the stomach together with food can reduce this damage, so antibiotic drugs for H. pylori should be taken after meals.
It is recommended that patients under the guidance of a doctor to carry out regular treatment, not self-medication, so as not to cause adverse consequences.