A fever of 37.5 degrees with headache may be caused by a cold or a central nervous system infection such as encephalitis. If the fever is caused by a cold, the patient may also have sore throat, cough and nasal congestion, and should be treated with anti-cold medications, such as cold capsules, cold flush, cold and fever pellets, Pancreatine pellets or Lianhua Qingfei capsules, or oral acetaminophen if the headache is severe. If encephalitis is considered, EEG should be checked further and cerebrospinal fluid should be extracted for pathogenic examination if necessary. If it is encephalitis, antiviral therapy should be given, often clinically with acyclovir, along with cranial pressure lowering therapy, such as mannitol and glycerol fructose. Nutritional therapy can also be given, usually with vitamin B, etc.