Skin allergy occurs, may cause hives, contact dermatitis, drug rash and other diseases, first of all, we should pay attention to avoid contact with possible allergic substances, while oral anti-allergic drugs for treatment. 1. Avoid contact with potentially allergic substances: If the patient is allergic to a certain food or drug, it is recommended to stop eating it and avoid eating it again. Allergen testing can also be used to find allergens, and desensitization can be done if there is a clear allergen. 2. Oral anti-allergy drugs: Oral antihistamine anti-allergy treatment, such as chlorpheniramine maleate, loratadine, etc.; patients with severe symptoms, can follow the doctor’s instructions to systematically apply glucocorticoids such as prednisone to carry out the treatment, and, if necessary, can be used under the guidance of the doctor, such as cyclosporine and other immunosuppressants to carry out the treatment. Patients with skin allergies are advised not to scratch with their hands during the treatment period, not to eat spicy and stimulating food, and to consult the dermatology department of regular hospitals in a timely manner.