Red spots on the legs may be related to hives, fungal infections, eczema, and psoriasis, etc. Depending on the disease, the itching can be improved by the following methods, mainly medication. 1. Urticaria: Urticaria will appear as red spots in the form of wind clouds with intense itching. Most of the patients will subside in 24 hours or so, if not, you can take chlorpheniramine maleate tablets, tretinoin tablets and other oral treatment, and pay attention to keep away from allergens in life. 2. Fungal infection: Typical symptoms are local skin rash, itching on the surface of the rash, and local skin thickening and color deepening. Anti-fungal drugs can be used for external treatment, commonly used drugs are bifonazole cream, terbinafine hydrochloride cream, etc., and in serious cases, oral itraconazole capsules and other drugs. 3. Eczema: Eczema will appear as reddish papules or pimples, which can be treated with oral loratadine tablets and cetirizine hydrochloride tablets, and localized glycerine lotion for relief, and at the same time, pay attention to keep away from allergens. 4. Psoriasis: psoriasis is a chronic inflammatory skin disease, manifested as erythema of the skin, erythema of varying sizes and covered with silvery-white scales, which can be treated with Avicenna capsules, methotrexate tablets, cyclosporine, and other biologics such as stauchytolimus and topical medicines such as hormonal ointment, retinoic acid ointment, vitamin D3 derivatives and other medicines. Erythema on the legs due to the complexity of the cause, it is recommended that patients seek medical attention in a timely manner to clarify the cause, according to the cause of the disease, and strictly comply with the doctor’s instructions for treatment.