Intestinal tuberculosis and intestinal cancer, these two diseases are different in concept, clinical symptoms and treatment. 1. Different concepts: intestinal tuberculosis is a chronic specific infection of intestinal tract caused by tuberculosis mycobacteria, secondary to pulmonary tuberculosis; intestinal cancer is a common malignant tumor of digestive tract, usually refers to colorectal cancer. 2. Different clinical manifestations: patients with tuberculosis of intestines may have abdominal pain, abdominal mass, change of bowel habit, long-term irregular low-grade fever, emaciation, night sweating (sweating abnormally after going to sleep, and sweating stops after waking up), fatigue and other systemic symptoms. Early stage of intestinal cancer may have no obvious symptoms, but with the development of the disease, there may be changes in the character of stool, such as mucus stool, blood stool, urgency and heaviness (discomfort in the lower abdomen, wanting to relieve stool, feeling of incomplete defecation after defecation), etc., and there may be changes in the habit of defecation, etc. There is no night sweating and other manifestations of tuberculosis toxicity in intestinal cancer. 3. Different treatment: intestinal tuberculosis is mainly treated with anti-tuberculosis chemical drugs, commonly used drugs are isoniazid, rifampicin, streptomycin, etc. Patients should follow the doctor’s instruction of early, regular and full medication. Patients should follow the doctor’s instructions for early, regular and full medication. For those who meet the indications of surgery, resection and anastomosis of intestinal segments can be carried out. Early-stage intestinal cancer can be cured through surgery, while middle and late-stage intestinal cancer requires comprehensive treatment, mainly surgery, with postoperative adjuvant chemotherapy, radiotherapy or targeted therapy to prolong the survival period of patients.