Duloxetine combined with olanzapine treatment is possible, but under the guidance of a doctor to use the drug correctly. Duloxetine is a kind of antidepressant drug, commonly used in the treatment of depression and anxiety disorders, duloxetine drug adverse reaction is less, long-term use can reduce the recurrence of depression symptoms, after taking the drug may appear dizziness, vomiting and other side effects, for liver function abnormalities, renal function abnormalities of the patient should be careful to use this drug, stop the drug more often to take a gradual reduction of the dose of discontinuance of the way. Olanzapine is an antipsychotic drug, which has a better effect on the positive symptoms of schizophrenia, as well as moderate to severe manic episodes, and can also prevent the recurrence of bipolar disorder among mental problems. Side effects of olanzapine are sedation and effects on metabolism, and may include drowsiness, increased blood sugar and lipids, and weight gain. It should be used with caution in women who are pregnant and breastfeeding. Duloxetine combined with Olanzapine should be taken in doses under the supervision of a doctor in order to achieve a better therapeutic effect of the disease, do not combine drugs on your own.