The best drug to relieve acute myocardial infarction, severe pain symptoms is nitrate drugs. In the clinic, try to choose short-acting preparations of nitrate drugs, such as the choice of static nitroglycerin, depending on the actual severity of the patient’s pain, you can speed up the speed of intravenous infusion. But in the application of this drug at the same time, must pay attention to monitoring blood pressure as well as heart rate. For patients with hypotension, this drug is relatively unsuitable for improving pain symptoms. Along with nitrates, patients can also receive subcutaneous injections of low molecular heparin, as well as chewable aspirin, clopidogrel, atorvastatin, and other types of medications, which can help to further improve the sensation of pain. If there is an emergency coronary angiography procedure, it is recommended that the patient can combine this with chewable Tegretol instead of clopidogrel, which is relatively faster-acting and has a stronger antiplatelet effect.