Ultrasound suggests diffuse enhancement of intrahepatic echogenic spots indicating the presence of acute and chronic hepatocellular injury, which may indicate viral hepatitis, fatty liver, and alcoholic liver disease. 1. Viral hepatitis. Hepatitis virus damages hepatocytes, causing some hepatocytes to become deformed and necrotic, and the necrotic hepatocytes will appear point-like diffuse enhancement under ultrasound. Viral hepatitis can be diagnosed by combining with serum hepatitis virus antigen antibody and other tests. 2. Fatty liver. Diffuse echo spot enhancement may also indicate fatty liver, and the fat droplets deposited in fatty liver may also appear similarly in ultrasound. The diagnosis of fatty liver can be confirmed by the combination of the patient’s body type and blood lipid levels. 3. Alcoholic liver disease. If the patient has a history of chronic alcoholism, it is also important to consider whether the hepatocellular necrosis is due to excessive alcohol consumption. It is recommended that patients with diffuse intrahepatic echogenic point-like enhancement should seek prompt medical attention and complete the relevant investigations to determine the cause of the disease before deciding on the next course of treatment.