Lower limb or circumferential flaccid paralysis is a symptom of the aqueous salt metabolism disorder type of Barth syndrome. So, what are the differential diagnoses of lower limb or peripheral flaccid palsy? This question is introduced as follows: Differential diagnosis of lower limb or peripheral weakness: 1. Lower limb weakness: Lower limb weakness is mostly caused by spinal cord type cervical spondylosis, manifested as lower limb weakness, numbness, tightness, heavy feeling of lifting steps and other symptoms, and gradually limping, trembling, swaying gait and easy falling. Spinal cord cervical spondylosis is a type of cervical spondylosis. Cervical spondylosis can be broadly divided into four types: cervical cervical spondylosis, neurogenic cervical spondylosis, vertebral artery cervical spondylosis, and spinal cord cervical spondylosis. Cervical spondylosis, also known as cervical spine syndrome, is a general term for cervical osteoarthritis, proliferative cervicitis, cervical nerve root syndrome and cervical disc prolapse, and is a disorder based on degenerative pathological changes. 2.Swelling and weakness of lower limbs: swelling and weakness of lower limbs is one of the symptoms of deep vein thrombosis. 3.Muscle paralysis of lower limbs: muscle paralysis of lower limbs is a symptom of spinal cord compression disorder. 4, generalized dystonia: Dystonia refers to a movement disorder disease characterized by abnormal muscle tone movements and postures caused by uncoordinated or excessive contraction of active and antagonistic muscles. The most severe form of the disease shows an unforgiving and steadily progressive course, and cases with very severe symptoms may often be in a peculiar fixed posture formed by total body torsion. Mental and thinking functions usually remain normal.