Unexplained pain in the ribs, generally there may be the following three situations: First, the recurrence of old injuries, there may have been a rib contusion or chest soft tissue contusion in the past, at that time, due to a variety of reasons did not seriously and thoroughly treatment, resulting in the pain to reappear. Second, costochondritis or mild hyperplasia of the rib cartilage, so that local pain appears, may be accompanied by mild swelling, also more common in the clinic. Third, intercostal neuralgia, manifested as no change in the local appearance, there is no history of injury, the pain may be intermittent or recurrent. These three cases of rib pain are very common in the clinic, and it is difficult to identify them, or they may exist at the same time. There is no positive change in chest X-ray or CT examination. Clinical treatment is mainly based on rest, reducing activities, prohibiting local pressure and rubbing and other stimuli that may hinder the recovery, local physical therapy, topical application of sprays or ointments that activate blood circulation and dissipate blood stasis, and oral analgesic medication to alleviate the pain. For the diagnosis of clear intercostal neuralgia can make the effect of local closure satisfactory, for many patients with chest pain for no reason, in the case of a variety of tests and treatments without positive lesions, should actively do a good job in the patient’s psychological guidance, relieve the patient’s nervousness, reduce the ideological pressure, eliminate the patient’s doubts, and is conducive to the patient’s early recovery.