The saddle region is an anatomical structure in the brain that normally houses the pituitary gland. Saddle region occupancy refers to the development of a space-occupying disease in the saddle region, usually referred to as a tumor. Benign tumors are more common in the saddle region, the most common being pituitary tumors, others include meningiomas, craniopharyngiomas, and malignant ones such as gliomas. Pituitary tumors originate from the adenopituitary gland, and in addition to occupying lesions, they often lead to endocrine hormone abnormalities, which often lead to hormone abnormalities in the hospital, and then to pituitary tumors. Meningiomas, on the other hand, are mainly manifested by compressive lesions, which may lead to visual abnormalities and optic nerve damage. Gliomas are more malignant and may be prone to recurrence after surgery.