How long will polycystic kidney become uremia should be discussed from the following two aspects, polycystic kidney is divided into two types of autosomal recessive polycystic kidney disease and autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney disease, the progression of renal failure is slower, before the age of 15 years old, 20%-45% of the children will progress to uremia, and before the age of 25 years old, 70% of patients will enter the uremic stage. For autosomal dominant polycystic kidney disease, the progression to uremia is relatively slower, with about 50% of patients over 60 years old entering the uremic stage. Overall, for patients with autosomal dominant polycystic kidney disease, the time from impaired renal function to the development of uremia is several decades.