Spots on the hands, may seborrheic keratosis, may also be long-term sun exposure or exposure to irritants caused by hyperpigmentation. As people get older, human skin will form seborrheic keratosis, manifested as brown spots or plaques with clear boundaries, and the surface can be cerebral gyrus-like, which is a benign disease that generally requires no special treatment or therapy. However, if long-term exposure to chemical irritants, or long-term exposure of the hands to ultraviolet light, more and more hyperpigmentation may also form. In this case, you should consult a dermatologist and avoid sun exposure and pay attention to the daily protection of your hands. If you come into contact with chemicals, it is recommended that you wear gloves, and if you are exposed to the sun for a long period of time, it is recommended that you wear sunscreen. Usually to strengthen the hand skin care, you can apply Vitamin E cream, hand cream and other medicines, skin care products to strengthen the skin moisturizing. The phenomenon of long spots on the hands, should promptly consult a doctor to identify the cause of the disease, under the guidance of a physician to use medication.