Vitiligo healed for more than ten years may still recur. Vitiligo is mainly due to genetic factors, autoimmune, oxidative stress and other reasons, the main clinical manifestation of white spots or (and) white hair, and any part of the body can be affected. Because vitiligo has recurrence, so some patients with vitiligo healed more than ten years may still recur, but the treatment can still get some effect. Patients should pay attention to skin protection in daily life, avoid strong sunlight exposure, and pay attention to do not scratch, scrub the skin. Strictly follow the doctor’s instructions for medication, learn the correct use of drugs, avoid indiscriminate use or abuse of drugs. It is recommended that patients with vitiligo recurrence go to the hospital in time for treatment, to avoid delaying the condition.