Cough with phlegm and sore throat may be caused by acute pharyngolaryngitis, acute bronchitis, etc., and need to be treated with antibiotics, cough and phlegm medication according to the cause and degree of symptoms. 1. Acute pharyngolaryngitis: when the throat area is stimulated by inflammation for a long time, edema, increased secretion, there may also be a cough with phlegm, sore throat symptoms, can contain loquat loquat tablets, watermelon cream, etc., the use of budesonide suspension nebulized inhalation treatment, oral penicillin G, penicillin V and other antibiotics. 2. Acute bronchitis: patients in the exacerbation period will have a violent cough, which leads to edema and congestion of the throat, causing coughing, coughing up sputum and sore throat and other symptoms. Need to use aminobromine hydrochloride, snake gall and Sichuan shellfish liquid and other cough medication, the use of amoxicillin capsules, cefadroxil capsules and other antibiotic treatment. Cough phlegm sore throat cause is more complex, need professional doctor guidance for targeted medication and treatment, do not self-medication.