Tingling and itching in the palm of the hand may be caused by localized pressure, cervical spondylosis, carpal tunnel syndrome, allergic reaction, etc., which need to be treated with medication or surgery according to the cause. 1. Localized pressure: prolonged pressure on the palms of the hands leads to poor local blood circulation, tissue ischemia and lack of oxygen and numbness and itching. You need to relax your hands to avoid localized pressure and apply hot compresses if necessary. 2. Cervical spondylosis: cervical vertebral hyperplasia and degeneration, cervical disc herniation and other factors lead to cervical nerve root compression, innervation of the palm of the hand part of the sensory dysfunction, so it will be numb and itchy palms. It can be treated by traction, acupuncture, physical therapy and other ways, and surgery if necessary. 3. Carpal tunnel syndrome: Various factors cause the lumen of carpal tunnel to become small, edema in the carpal tunnel, and the volume of the contents of the carpal tunnel increases, leading to compression of the median nerve in the carpal tunnel, so the palms of the hands are numb and itchy. Prednisone can be injected into the carpal tunnel for surgical treatment if necessary. 4. Allergic reaction: the contact with dander, seafood, hair, chemicals, dust and other substances on the surface of the skin induced allergic reaction, itchy palms, numbness, redness and other symptoms. Loratadine and other drugs can be applied to treat. Tingling and itching on the palms of the hands may be related to a variety of factors, it is recommended to consult a doctor for a clear diagnosis. Pay attention to the use of medication under the guidance of a physician.