Small blisters on the hands with itching in the summer are commonly seen clinically, usually as ringworm, followed by eczema, or sweat blisters. Tinea capitis is caused by a fungal infection, and in the blistering and scaling form, deep blisters develop between the fingers and palms, which gradually dry up and flake off. You can apply a fungus-inhibiting cream, such as terbinafine ointment, 2 times a day. Acute eczema, too, can appear on the hands as erythema, papules, and in severe cases, small blisters that may fuse into patches with not very clear borders and are accompanied by intense itching. Eczema, on the other hand, is an eczema-like hypersensitivity reaction that occurs on the skin of the hands and soles of the feet and is characterized by deep pinpoint to corn-sized blisters with itching. Eczema, as well as sweat blisters, are treated with the same medication, and can be treated with the application of mometasone furoate cream, combined with oral anti-allergy medication.