Oral white spots belong to the category of “callus lips” and “spots” in Chinese medicine, which are mostly related to Qi stagnation and blood stasis, phlegm-dampness coagulation, and Qi-blood disharmony according to Chinese medicine, and can be treated with Chaihu Shuohe San and Taohong Siwu Tang, Ercheng Tang Plus Flavor, and Ginseng Ling and Atractylodes Macrocephalae San and GuiSpleen Soup and other drugs. The treatment may include the following drugs. Spleen qi deficiency, blood transportation weakness, congestion of qi and blood, accumulation and non-dispersion, forming white spots. Treatment may include Chai Hu Shuo Liver San combined with Tao Hong Si Wu Tang, which is used to dredge the liver, move qi and activate the blood to resolve the spots. Spleen dysfunction (dysfunction of the spleen’s transportation function), gathering dampness as drink, drink condensation into phlegm, phlegm and evil gathering, knotting in the mouth, resulting in white spots. For treatment, Er Chen Tang can be used to dissolve phlegm and dry dampness, resolving condensation and resolving spots. Injury to qi and blood caused by prolonged illness, the mouth muscle loses moistening, resulting in leukoplakia. For treatment, ginseng ling and white artemis powder combined with gui shu tang can be used to nourish blood, strengthen the spleen and remove stagnation to resolve spots. After the appearance of the above symptoms should be timely consultation, under the guidance of a professional physician to identify the use of the above drugs, the adverse effects of the above drugs or contraindications are not yet clear, do not use on their own, so as not to cause damage to the organism.