Post-transfusion chills and fever should first be stopped immediately and then receive targeted treatment. Post-transfusion chills and fever are related to infection caused by contamination of transfusion equipment and blood by pyrogen and failure of aseptic operation, and may also be caused by acute hemolysis due to heterogeneous blood or multiple transfusions.
1. After being infected by a pyogenic source and causing chills and high fever, first of all, blood transfusion should be stopped immediately, and then the patient should be observed dynamically, and physical cooling or analgesic drugs such as cotrimoxazole can be used.
2. Acute hemolysis can be caused by blood group incompatibility, overloading of recipient’s body due to long-term blood transfusion, or corresponding antibody in recipient’s body, which can be manifested as chills, fever, chest pain, respiratory distress, hypotensive shock, etc. The patient should immediately stop the transfusion.
Blood transfusion should be stopped immediately, apply high-dose glucocorticoid (methylprednisolone), alkalinize urine and diuretic (sodium bicarbonate, furosemide), and perform dialysis, plasma exchange or blood exchange therapy if necessary.
After the transfusion of blood discomfort should immediately stop the transfusion, the doctor to determine the condition and give the corresponding treatment, the above drugs need to be used in accordance with the doctor’s instructions.