Excessive estrogen will cause excessive growth of endometrium, heavy menstruation, menstrual disorders, uterine fibroids and other diseases for women; for men, it will cause voice thinning, breast development and other feminized signs. 1. Women: Since estrogen will stimulate endometrial proliferation, endometrial thickening, endometrial polyps, endometrial hyperplasia and even cancer will occur. In addition, it will stimulate abnormal follicular development, resulting in excessive menstrual flow, irregular menstruation, and abnormal ovulation; at the same time, a high level of estrogen will promote the occurrence and progress of uterine fibroids, breast nodules, adenomyosis and other diseases. 2. Men: High estrogen levels in men are often seen in patients with severe liver disease. Abnormalities in liver function will affect the metabolism of estrogen, which in turn will lead to changes in physical characteristics such as thinning of the voice, breast development, loss of libido, and reduction of the beard. For patients with high estrogen levels, it is recommended to go to the endocrinology department of regular hospitals, gynecology and other consultations in a timely manner, to clarify the cause of the disease under the guidance of the doctor to actively treat, do not blindly use their own medication, so as not to delay the aggravation of the condition.