Oral antiviral medications for herpes zoster should be started 24 to 72 hours after the onset of the rash for a period of 7-10 days. The duration and dosage of antiviral medications for herpes zoster do not change due to secondary infections, and targeted treatment is sufficient in the presence of infection. Herpes zoster is a skin disease caused by varicella zoster virus infection, the clinical mainly to antiviral drug treatment, generally in the rash within 24 to 72 hours after the beginning of the use of antiviral drugs, secondary bacterial infections can be used with topical antibiotic treatment, but the antiviral drugs should be used in accordance with the original course of treatment. Infections can be treated with topical antibiotic ointment such as erythromycin ointment and mupirocin ointment, and if the infection is generalized and serious, antibiotics can be used systematically as prescribed by the doctor. Shingles infection should go to the hospital in time, the drugs need to be used under the guidance of a professional doctor.