A lower blood pressure of more than 100mmHg, generally referred to as diastolic blood pressure of more than 100mmHg, may lead to heart disease, stroke, fundus lesions, hypertensive nephropathy and other hazards. Normal blood pressure is diastolic blood pressure at 60-79mmHg and systolic blood pressure at 90-119mmHg. If the diastolic blood pressure exceeds 100mmHg, regardless of whether the systolic blood pressure is normal or not, it may be grade 2 or even grade 3 hypertension, which may lead to heart disease, stroke, fundus lesions, hypertensive nephropathy and other complications. 1. Heart disease: diastolic blood pressure exceeding 100mmHg for a long time will lead to left ventricular hypertrophy, which means causing hypertensive heart disease. In turn, it may lead to left ventricular coronary artery extrusion and stenosis, triggering myocardial ischemia, or even myocardial infarction, heart failure, etc. It may also induce various types of arrhythmia. 2. Stroke: including cerebral infarction, cerebral hemorrhage and so on. Diastolic blood pressure exceeding 100mmHg for a long time may lead to plaque detachment in cerebral arteries and trigger cerebral infarction. When the blood pressure rises again, it may cause cerebral hemorrhage of the patient, which is manifested as severe headache, coma, drowsiness, or even cerebral hernia due to the increase of intracranial pressure, and eventually the patient’s life will be in danger. 3. Fundus lesions: diastolic blood pressure exceeding 100mmHg for a long time will lead to arteriosclerosis, stenosis, infarction, exudation and hemorrhage of the fundus, which can lead to loss of vision or even sudden blindness. 4. Hypertensive nephropathy: long-term high blood pressure can also cause renal arteriosclerosis, renal insufficiency, proteinuria, which can eventually lead to uremia if not treated in time. If there are blood pressure abnormalities, it is recommended to consult a doctor as soon as possible, under the guidance of the physician treatment, to avoid delaying the condition.