Side effects such as dizziness, nausea, vomiting, fatigue, occasional tachycardia, edema, flushing, cough, diarrhea, dyspepsia, and other discomforts can occur with Irbesartan. Irbesartan is a common clinical long-acting antihypertensive drug used in the treatment of essential hypertension and type 2 diabetic nephropathy combined with hypertension. Irbesartan can be taken to dizziness, nausea, vomiting, fatigue and other side effects, occasionally tachycardia, edema, flushing, cough, diarrhea, indigestion and other discomforts. Irbesartan should be taken with care to correct blood volume insufficiency and/or sodium deficiency before starting treatment; patients with renal insufficiency should pay attention to changes in blood urea nitrogen, serum creatinine and blood potassium. Irbesartan is contraindicated in persons with known hypersensitivity to the components of Irbesartan, in the 4th to 9th month of pregnancy, in breastfeeding diabetes mellitus, or with moderately severe renal impairment Irbesartan should not be used in combination with aliskiren; it should not be used in combination with angiotensin-converting enzyme inhibitors in patients with diabetic nephropathy. Irbesartan should be taken under the supervision of a doctor, and if any of the above discomforts occur, seek medical attention immediately.