Shingles does not get better when the blisters rupture. The course of shingles is about 2 weeks, and when the blisters dry up and crust off while the pain subsides, it indicates that the shingles has gotten better. Herpes zoster is caused by varicella-zoster virus infection, the blisters can easily break, pay attention to local care, can be treated with topical iodophor solution, penciclovir gel, but mainly oral antiviral medication, such as vaxilovir or famciclovir oral. In severe cases, acyclovir can be given as a spot treatment, and attention must be paid to the combination of nerve-nourishing drugs and pain medication for those with significant pain. If the pain remains after the herpes zoster rash has completely subsided, it may be post-herpetic neuralgia, which can be treated with drugs such as doxepin and gabapentin.