If you have a pimple on your labia, the pimple is red, swollen and painful, often caused by vulvar boils and inflammation, and can be treated with Pepto-Bismol. If the pimple is grayish white, like a cauliflower, it is often caused by human papilloma virus infection of warts, which cannot be treated well by applying creams only. If you have a pimple on your vulva, it may also be caused by a herpes simplex virus infection, which needs to be treated with acyclovir ointment. It is best to go to the hospital for a clinical examination after a pimple on the labia, and then give the appropriate medication or treatment after diagnosis, so that the real treatment can be achieved.