Pimples, which are clinically known as acne, which turn into hard bumps, are considered to be suffering from severe stages of acne such as the formation of nodules, or due to diseases such as boils. Depending on the cause, patients can be treated in different ways, such as general treatment, medication, and surgery. 1. Acne: Acne patients can use retinoids such as retinoic acid cream and adapalene gel to apply to the affected area to kill bacteria, inhibit inflammation, unclog pores, and improve follicular sebaceous gland duct keratinization. For inflammatory acne, patients can be treated with topical benzoyl peroxide cream. Nodules and other severe stages can be treated with oral isotretinoin capsules. 2. Boils: Topical erythromycin and fusidic acid can be used to promote recovery. If the boil is purulent, you can also follow the doctor’s instructions to use 20% ichthyol ointment and other antiseptic drugs for topical treatment, to achieve the effect of antiseptic, antibacterial, antipruritic, and if the inflammation subsides after the nodule persists for a long time, it can be surgically excised if necessary. After the acne becomes hard pimples, it is recommended that the patient go to the hospital, clarify the cause of the disease, and follow the doctor’s instructions to use the appropriate way of treatment.