Taking rivaroxaban does not usually cause toothache and mouth swelling. If you feel a strong correlation, it is recommended to stop taking it and seek medical attention. Rivaroxaban is primarily a medicine for the treatment of venous blood clots in adults. The most common side effects are bleeding, upper abdominal pain, indigestion, toothache, blood clotting abnormalities, osteoarthritis, etc. It is a relatively safe anticoagulant. There is generally no obvious relationship between toothache and swelling of the mouth and oral intake of ordinary drugs. Toothache face swelling is mostly seen in odontogenic interstitial infection. Toothache is often due to dental caries is not timely treated, resulting in bacterial infection of the dental nerve appear acute reaction. Toothache and swollen mouth are mostly seen in interstitial infections of bacterial infection origin, which generally have no obvious relationship with oral medications, but drug-induced allergic reactions cannot be ruled out. Drug allergic stomatitis can cause pain and swelling. Prompt medical treatment is needed. Toothache and swelling of the mouth caused by taking rivaroxaban, if there is no dental disease itself, it is considered that it may be a drug allergy or other factors, and it is recommended to seek medical treatment in time. If you are suffering from dental related diseases, the swollen and painful mouth caused by teeth, it is recommended to consult a dentist in time to avoid serious gap infection.