The closed eye test is mainly used to check the ataxia function, and has clinical significance in checking the sense of movement and position. There are many diseases indicated by a positive Eyes Closed Difficulty Sign, which can be analyzed according to the patient’s other specific symptoms, and then considered in conjunction with the results of other reports of the patient’s disease. 1. Sensory ataxia: A positive Eyes Closed Difficulty Sign is characterized by a lightness of the eyes when the eyes are open and an aggravation of the eyes when they are closed when performing the ataxia examination, and a lack of tuning fork vibration sensation and joint positional sensation, and a lack of the ability to stand bipedally with the heels open but wobbly or fall down when the eyes are closed. Cerebellar ataxia: If the patient can stand bipedally with both hands stretched forward, and the body shakes and swings back and forth when the eyes are open or closed, it is called cerebellar ataxia, which suggests cerebellar lesions. It is commonly seen in children with cerebellar medulloblastoma, chronic diffuse cerebellar atrophy or cerebellar infarction vascular disease, etc.; 3. Vestibular ataxia: if the patient tilts to the side of the lesion, it suggests that one side of the vestibule is damaged, which is often accompanied by vertigo, vomiting and nystagmus, and the change of the head position can aggravate the symptom, which can be seen in the acute inner ear disease, such as hemorrhage of the inner ear, acute inflammation of the inner ear.