HPV negative, indicating no infection with HPV virus, reactive cell changes, it indicates that may have cervicitis and some other diseases. HPV refers to human papillomavirus, HPV low-risk type can cause the proliferation of squamous epithelium of human skin and mucous membranes, and its main symptoms are genital warts or common warts, etc. HPV high-risk type can lead to cervical lesions or even cervical cancer. In the relevant examination, if the HPV is negative, it means that the examinee is not infected with the virus and is relatively safe. Reactive cell change is a result during TCT examination, which indicates that the patient’s cervix has been attacked by pathogenic bacteria, causing cell change, and further relevant examination is needed to clarify the specific cause and then carry out targeted treatment. It is recommended that patients should maintain good pubic hygiene in their daily life, avoid unclean sex, and undergo regular screening for cervical cancer, so that early treatment can be carried out when problems are found.