Impotence generally refers to erectile dysfunction, generally in clinical practice, erectile dysfunction combined with premature ejaculation patients can take 5 hydroxytryptamine reuptake inhibitors, type 5 phosphodiesterase inhibitors, and androgenic drugs, etc., may work. Patients with erectile dysfunction may experience symptoms such as slow erection, difficulty in erection, weakness before ejaculation, and premature ejaculation in some patients. Patients with erectile dysfunction who experience premature ejaculation need to take oral dapoxetine, paroxetine, sertraline, and other 5-hydroxytryptamine reuptake inhibitors under a doctor’s supervision. If there is a lack of penile hardness, you need to take oral phosphodiesterase type 5 inhibitors, such as sildenafil, vardenafil, tadalafil and so on, as prescribed by the doctor. Or oral androgenic drugs, such as testosterone undecanoate gel pills. After standardized drug treatment, some patients may work. Once patients with erectile dysfunction have premature ejaculation, they need to consult a doctor promptly. Under the guidance of the doctor to take relevant therapeutic measures, so as not to delay the condition. At the same time, in the daily can keep local clean and clean, so as to avoid secondary infection. Ensure sufficient sleep, do not overwork.