The symptoms of hepatic coma mainly consist of symptoms of neuropsychiatric dysfunction such as agitation, apathy, lethargy, coma, etc., and there may also be signs such as fluttering tremor and abnormal nerve reflexes. Symptoms of hepatic coma are mainly the dysfunction of the higher nerve center, which will have different degrees of manifestation in stage 0~4. 1. The latent stage (stage 0) often has no abnormal symptoms such as behavior and character. 2. Prodromal stage (stage 1) may show mild personality changes and mental abnormalities, such as anxiety, agitation, euphoria or indifference and forgetfulness. 3. Pre-comatose stage (stage 2) may have symptoms such as drowsiness, behavioral abnormalities such as disheveled clothing or urinating and defecating, dysgraphia, and slurred speech. 4. Coma stage (stage 3) may have symptoms of lethargy, which can be awakened, and may also have delirium, hallucinations and other manifestations. 5. Coma stage (stage 4) manifests coma and is difficult to wake up. In addition to abnormal neuropsychiatric and behavioral symptoms, hepatic coma also has signs such as fluttering tremor, muscle tone, and abnormal tendon reflexes, etc. These clinical signs should be treated promptly.