Cold and flu with pus runny nose is a very common phenomenon, which can be dealt with by the following methods: 1. Use saline dipped cotton swabs to clean the nasal cavity, remove the pus nasal discharge and relieve the symptoms of nasal congestion. 2. Use histamine drugs under the guidance of a doctor to relieve the production of nasal mucus. If the patient is accompanied by symptoms of cough and sore throat, you can also choose a combination of drugs to relieve the symptoms, such as compound aminophenol alkylamine and other drugs. 3. Check the blood picture, if the patient’s blood picture is elevated, indicating the existence of bacterial infection, can be treated by using antibiotics, such as penicillin or cephalosporin. If the patient does not get better for a long time, he needs to go to the hospital for further consultation. At the same time, we should pay attention to keep warm, drink more hot water, eat more fruits and vegetables.