1.Pain care Many patients with liver cancer will have liver pain, which makes many liver cancer patients have trouble sleeping and eating, what should they do? Late stage liver cancer can cause pain in tumor area due to necrosis of tumor tissue. Nurses should do a good job of comforting patients while strengthening the observation of the disease. When the pain is intolerable, closely observe the location, nature and degree of pain so as to distinguish it from pain caused by other complications, and if necessary, follow the medical prescription to stop the pain. 2.Psychological care The mood of patients in general is very bad, let alone liver cancer patients. When liver cancer patients reach advanced stage, they know they have reached the last stage of life and cannot accept the reality that they are going to lose their friends and relatives and leave the earth forever, coupled with the adverse reactions during the diagnosis and treatment and unbearable cancer pain, they often show great depression and anxiety, irregular life, lack of concentration, loss of appetite and fatigue. Psychological care, pain control, and improve the quality of patients in the last stage of life. 3.Basic care Relevant nursing work is needed for liver cancer patients in daily life so as to avoid the deterioration of liver cancer patients’ diseases. Patients with advanced liver cancer are weak, so basic care should be strengthened, such as for patients who have been resting in bed for a long time, they should turn their backs and change their sitting and lying positions to prevent complications such as bedsores; for patients with bleeding, they should do a good job of oral care to keep the respiratory tract unobstructed to prevent asphyxiation caused by vomit. For patients with severe cancer pain, besides timely symptomatic treatment, family members should also give spiritual comfort to eliminate patients’ fear, and at the same time closely observe patients’ vital signs to detect critical lesions in time and take effective treatment measures. In particular, the diet of advanced liver cancer should pay attention to the color, aroma and taste of food to enhance the appetite of patients with advanced liver cancer. Patients with advanced liver cancer can consume some Chinese porridge, such as Astragalus porridge, Radix et Rhizoma ginseng, red date porridge, etc., which can nourish the spleen and benefit the qi. Do not lie down half an hour after meal. Patients with advanced hepatocellular carcinoma are forbidden to eat greasy or fried food. Anti-emetic agents can be given to those who vomit, and if necessary, total intravenous nutrition support can be given. Patients with advanced hepatocellular carcinoma should restrict or forbid protein when the blood ammonia is high. The heat source of patients with advanced liver cancer is mainly sugar, and fruits and vegetables can be used.