Medications are preferred for the treatment of trigeminal neuralgia, and new drug advances include eslicarbazepine acetate, lamotrigine, and mesylate.
1. Eslicarbazepine Acetate: Similar in chemical structure to Carbamazepine, it is a derivative of Carbamazepine, but reduces the inactive components of Carbamazepine, thus increasing its efficacy. The therapeutic efficacy, safety and tolerability of eslicarbazepine acetate are greatly improved over carbamazepine.
2. Lamotrigine: Lamotrigine is a new type of antiepileptic drug that antagonizes recurrent abnormal discharges of the trigeminal nerve. There are studies that lamotrigine can quickly relieve patients’ pain symptoms, with ideal near-term efficacy and fewer adverse effects. When the adverse effects of carbamazepine are severe or the symptoms are not well controlled, lamotrigine can be used as a second-line treatment option for refractory trigeminal neuralgia.
3. Mexilette: Currently, lidocaine is used clinically mainly for the diagnostic treatment of trigeminal neuralgia. The antiarrhythmic drug mexiletine, which has a similar structure to lidocaine and is an oral dosage form of lidocaine, is widely used in the treatment of diabetic neuralgia, pain after peripheral nerve injury, and other
treatment of neuropathic pain. It has also been studied for the treatment of trigeminal neuralgia, but the long-term effects and adverse reactions require further study.
If trigeminal neuralgia occurs, you should go to the hospital for consultation and treatment, and use the medication in accordance with the doctor’s instructions, avoiding self-medication.