Patients with migraine headaches are required to undergo a cranial CT. Migraine is a vascular-neurologic headache and is a very common type of primary headache. Migraine patients mostly experience a throbbing frontal-temporal pain on one side of the head, and the pain can be moderate to severe. Migraine attacks are related to genetic, endocrine, dietary and environmental factors. Diagnosis of migraine relies on the patient’s medical history and clinical presentation, while cranial CT and cranial magnetic resonance are exclusion criteria for migraine. The above tests are done to exclude intracranial tumors, hemorrhage, inflammation and other diseases, and provide the necessary differential for the diagnosis of migraine. Therefore, migraine patients need to have a brain CT or MRI.