Usually, drinking cola after eating shrimp does not cause toxic reactions, but it can cause digestive system adverse reactions such as infectious diarrhea. Shrimp contains a lot of protein, and cola contains cocoa butter and caffeine. Drinking cola immediately after eating shrimp will increase the effect of osmotic diarrhea, and there will be, for example, abdominal pain, periumbilical colic, bloody stools, dilute watery stools, increased frequency of diarrhea, watery stools, and irregular stools, all of which are clinical symptoms and reactions of infectious diarrhea. In addition, although drinking cola after eating shrimp does not cause poisoning, upper gastrointestinal symptoms such as acid reflux, heartburn, nausea, vomiting and other irritating reactions may occur, so it is not recommended to drink cola immediately after eating shrimp.