Upper heat and lower cold (upper heat, lower cold) refers to the upper part of the manifestation of heat, the lower part of the manifestation of cold symptoms, can be in the physician under the guidance of the diagnosis of drugs such as wu mei pill, Jiaotai pill. 1. Wu Mei Pill: mainly composed of Huang Bai, fine Xin, Wu Mei meat, Gui Zhi, dry ginger, pepper and other drugs, has the effect of clearing the upper and warming the lower part of the body, slowing down the liver and regulating the middle part of the body, and can be used for the treatment of syncopal headache (headache caused by disease evils invading the syncopal meridian), prolonged dysentery, roundworm syncope, and so on. It should be used with caution for those with cold or heat evidence of ascarid syncope, and those with prolonged dysentery due to deficiency and coldness of the spleen and kidney. Kidney disease patients, pregnant women, newborns are prohibited. 2. Jiaotai Pill; mainly composed of two Chinese medicines, Huanglian and Cinnamon, has the effect of communicating with the heart and kidney (the fire of the heart descends and the water of the kidney rises, which is a mutual restraint), and can be used for the treatment of the cardiac and renal hyperactivity, cardiac and renal dysfunction (cardiac and renal fire, renal yin deficiency, and dysfunction in the physiological functions of the heart and the kidney), which can be seen as restlessness at night, and mouth and tongue sore, etc. The adverse reactions and contraindications are not known. Its adverse reactions and contraindications are not clear. The above medicines should be used under the guidance of Chinese medicine practitioners, and should not be taken blindly by oneself to avoid damage. If there is any discomfort, please consult the doctor in time.