Mycoplasma urealyticum is examined by taking urethral or vaginal secretions. The procedure is as follows: a medical swab is inserted near the urethral or vaginal opening and a small amount of secretion is taken by gentle rotation and placed in a clean test tube and then promptly sent to the laboratory for examination. Bacterial culture and drug sensitivity tests can be done to determine the infection of Mycoplasma urealyticum based on the test results and then further treatment. Mycoplasma urealyticum infection can lead to non-gonococcal urethritis or vaginitis, which can cause clinical symptoms such as frequent urination, urgent urination, painful urination with thin discharge. And it also has an effect on the semen of men, which may lead to sperm malformation and decreased vitality. Therefore, once diagnosed as positive for Mycoplasma solani and with obvious clinical symptoms, timely treatment should be carried out, and macrolide antibiotics such as azithromycin and roxithromycin can be chosen for treatment.