Puffy face may be caused by physiological factors, such as staying up late, pay attention to rest can be relieved, may also be disease factors chronic nephritis, cardiac insufficiency, such as chronic nephritis caused by can take captopril medication, cardiac insufficiency with hydrochlorothiazide medication. 1. Physiological factors: if the night before rest is not very good, stay up late or drink more water, there will be the phenomenon of face swelling, which is a physiological factor, just need to pay attention to rest, reduce the amount of drinking water, the phenomenon of face swelling can be improved. 2. Chronic nephritis: chronic nephritis can cause decreased renal excretion of sodium and water, resulting in sodium retention, increased extracellular fluid, increased hydrostatic pressure in capillaries, resulting in facial edema, the patient should avoid overwork, quit smoking, limit the consumption of alcohol, etc., you can also take Benadryl, furosemide and other medications to alleviate facial edema. 3. Cardiac insufficiency: patients with cardiac insufficiency mainly show swelling of the lower limbs and face, which is mainly caused by the obstruction of venous return of the heart, resulting in elevated venous pressure, and can be treated with diuretics, such as hydrochlorothiazide, spironolactone, etc., by improving the life style, abstaining from smoking and drinking, and having a low-salt and low-fat diet. It should be noted that the above drug treatment must be carried out under the guidance of a professional doctor, there are other causes of facial swelling, should be timely medical treatment of the cause.