The answer is of course yes. Filler materials for the face include collagen, hyaluronic acid, as well as autologous fat, granular fat, nano-fat, fat gel and so on. As far as my personal clinical practice is concerned, I think autologous fat is the best material at present. It is from our own body, not a foreign material, and for nasolabial fold filling, autologous fat is a material I often recommend. Although fat glue is the purification of autologous fat, the purification rate is relatively low, the purification process is relatively long, and the cost is relatively high, so it is recommended to choose according to the actual situation. Many candidates can’t tell when the nasolabial folds need to be lifted and when they need to be filled. If the nasolabial folds are a little superficial, and you are more concerned, you can do localized filling. If the nasolabial folds are a little shallow and you are concerned about them, you can do localized fillers. If the nasolabial folds are enlarged due to ageing, it is necessary to consider that it is caused by skin laxity, and it is recommended to have a facelift first, and then fill the nasolabial folds afterwards. Hyaluronic acid is not recommended as a filler material. Although hyaluronic acid is a commonly used material in medical aesthetics, it comes from outside the body and is often used for topical fillers. However, for nasal base fillers, hyaluronic acid has a certain degree of freedom, and if the filler is a little poorly done or has a little too much tension, it will slowly spread to the edges. Some candidates after filling hyaluronic acid, the nasolabial folds did not rise up, but other places higher, nasolabial folds appear deeper, which means that the hyaluronic acid appeared to shift, while for the autologous fat filling, this problem is rarely seen.