Neonatal fever 37.5 ℃ can be caused by physiological reasons, can also be seen in neonatal pneumonia, intracranial infection and other conditions, the intervention needs to be carried out according to the cause of the disease, such as bacterial meningitis need to be actively anti-infective, appropriate lowering of the cranial pressure and physical hypothermia and other treatments. 1. Neonatal pneumonia: it is a common infectious disease during the neonatal period, clinical symptoms such as elevated body temperature, moaning and spitting, chest X-ray can assist in the diagnosis of bacterial infections need to be considered in the treatment of active use of antimicrobial drugs (eg, cefotaxime) anti-infective treatment for hypoxia need oxygen therapy, elevated temperature can be appropriate to take the physical hypothermia, and monitoring of body temperature. Neonates are young, the development of various organs is imperfect, there is no safer antipyretic drugs, the treatment needs to be active on the cause of the treatment, to be better body temperature can be gradually relieved. 2. Intracranial infection: such as bacterial meningitis, clinical drowsiness, convulsions and other symptoms, lumbar puncture can help diagnosis. Treatment requires the use of antibacterial drugs (such as ceftazidime) anti-infective treatment, and the use of mannitol to lower the cranial pressure, as appropriate. 3. Other: the age of the temperature center is not well developed, such as in the crying, breastfeeding or wrapped in too thick and other circumstances to measure the temperature, may also occur, need to avoid the above factors again to measure the temperature correctly. Newborn fever of 37.5 ℃ recommended to actively consult a specialist physician to determine the assessment, and give reasonable treatment, do not self-medication.