The difference between the New Coronavirus nucleic acid test for nose poking and throat poking mainly lies in the site of sample collection and the sample itself. 1. Poke nose: also known as nasopharyngeal swab test, which mainly uses a sampling tool to sample at the nasal cavity, with the secretion of the nasopharynx as the specimen, generally speaking, the accuracy is higher. 2. Stabbing the throat: also known as oropharyngeal swabbing, mainly collects secretions from the oropharynx and uses this as the specimen. However, due to the possible presence of food residues, the accuracy will be affected to a certain extent, but it is easy to operate and is better accepted by the population. Although the two collection methods are different, the main detection principle is to detect the specific nucleic acid sequence of the virus, with higher sensitivity and accuracy, and can be used to confirm the diagnosis of neococcal pneumonia. Tip: “New coronavirus pneumonia” and “new coronavirus pneumonia” mentioned in this article have been renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.