Generally, as long as the two pairs of half suggests that the surface antibody is negative, it means that there is no immunity to hepatitis B. These people need to be vaccinated against hepatitis B. In particular, the following groups of people have a higher risk of hepatitis B infection and are called high-risk groups, so they should be vaccinated against hepatitis B. These people include: 1. medical workers, who often have to come into close contact with patients at work and may come into contact with patients’ body fluids and blood, so they should be vaccinated against hepatitis B The vaccine should be given to all newborns in accordance with the national requirement for free hepatitis B vaccination.