Walking foot blisters, generally speaking, according to the severity of the patient’s feet wear different degrees, clinically can take different treatment methods: First, if the patient’s feet wear is light, only accompanied by mild blister formation, suggest that the patient fully bed rest, avoid continuing activities, resulting in the aggravation of the foot injury, and at the same time to give the local vitality of the iodine gauze external disinfection, to promote self-absorption of the small blisters; Second, if the foot wear is serious, blister volume obviously increased, can be given after the puncture needle out to suction out the vesicle fluid within the blisters to avoid causing local infection and pain. Second, if the foot wear and tear is serious, the blister volume is obviously increased, can give the vitality of iodine disinfection is completed, the use of puncture needle out of the blister suction of the cystic fluid, puncture to avoid cutting the blister completely, so as not to cause local infection and pain, and then can be used in Jinhuangsan ointment local topical application, can promote faster recovery of the blisters and soft tissue infections.