Transaminase 45 down to 40 is normal. The normal value range for transaminases is 0 to 40 U/L, so a decrease in transaminases from 45 to 40 U/L is a decrease to the normal value range. Mild elevations of transaminases are generally not pathologically significant, while exponential elevations suggest liver abnormalities. Transaminases are found mainly in liver cells. If abnormalities occur, they may lead to liver cell damage and release of transaminases, which can lead to elevated concentrations of transaminases in the blood. Usually mild elevations are of no pathological significance and may be due to overwork, alcohol consumption, and irregular routine. If the aminotransferase level rises exponentially, it may be due to hepatitis, cirrhosis, etc., and requires medical treatment if necessary. If aminotransferases are mildly elevated, they can be reduced to normal by adjusting the diet, paying attention to rest, avoiding alcohol, etc., and reviewing the results on a regular basis.