Children with coughs and phlegm do not necessarily need anti-inflammatory medication to treat them, nor is there a question of what anti-inflammatory medication is most appropriate. If anti-inflammatory medication is needed, it usually depends on the pathogen of the infection. If there is a bacterial infection, antibiotics such as penicillin can be taken to treat it, and if there is a mycoplasma infection, drugs such as azithromycin can be taken to treat the infection. 1. Bacterial infections: For bacterial infections, it is best to determine the sensitive drugs through drug sensitivity tests. Before the results of the drug sensitivity test come out, you can take empirical treatment. General yellow pus sputum can take penicillin and other treatments; if it is mucus sputum predominantly, consider the infection of negative bacilli, you can use the third generation of cephalosporins such as cefixime. 3. Mycoplasma infection: Mycoplasma pneumonia is a common cause of cough in children, caused by Mycoplasma pneumoniae infection, which can be treated with azithromycin and other macrolide anti-infective drugs. There are other reasons for children to cough up phlegm, so it is recommended to consult a doctor in time to find out the reason and treat the cause. The above medication is in accordance with the doctor’s prescription.