Swollen and itchy eye blisters may be caused by allergic conjunctivitis, blepharitis, and eyelid eczema. 1. Allergic conjunctivitis: Allergic conjunctivitis may be caused by heredity, bacterial or microbial infections and so on. Patients will have symptoms such as itchy eyes, swollen eye blisters, burning sensation in the eyes and redness of the white eyeballs. Therefore, patients with allergic conjunctivitis will have symptoms of swollen and itchy eye blisters. 2. Blepharitis: Blepharitis is considered to be related to Staphylococcus aureus infection and blepharoplasty dysfunction. The patient will show the eyelid margin congestion, redness and swelling, eye burning sensation, tingling, eye itching and other manifestations. If the patient has blepharitis, there will be swollen and itchy blisters and other manifestations. 3. Eyelid eczema: Eyelid eczema is mainly related to allergy, the patient’s eyelid area will appear itching, redness, papules, small blisters and other symptoms. If the patient’s eyelid area has eczema, it will be manifested as swollen and itchy eye blisters. 4. Other: patients with swollen and itchy eye blisters may also be caused by contact dermatitis and insect bite dermatitis. If the swollen and itchy eye bubbles are severe or persistent, it is recommended to consult a doctor in time. The doctor will choose the appropriate treatment according to the patient’s condition.