Parents of infants and children with the following risk factors should pay close attention to them: 1. Family history of genetic diseases. 2. 2.Premature labor (gestational age 37 weeks), premature labor (gestational age 42 weeks). 3, Low birth weight (birth weight 2500 grams), huge children (birth weight > 4300 grams). 4. Intrauterine, intra- or post-partum asphyxia. Jaundice is too deep or jaundice does not go away for 20 days and hospitalization due to jaundice. 6, Neonatal period has suffered from moderate or severe infectious diseases; neonatal period 28 days weight gain of less than 250 grams. 7. The mother has metabolic diseases, infectious diseases, sexually transmitted diseases, various moderate or severe pregnancy complications and history of preeclampsia. 8. The mother has a history of abnormal pregnancy and delivery: 2 spontaneous abortions, perinatal death, birth defects and cerebral palsy, infertility, or the age at delivery is 35 years old for the first delivery and 40 years old for the second delivery. 9. The mother has suffered from viral infections in early pregnancy, taken drugs that have an effect on the fetus, been exposed to radiation, suspected teratogenic substances and occupational poisons, and has bad habits such as smoking (more than 10 cigarettes a day), drug addiction, alcoholism, and so on. 10. The birth mother has poor parenting (dull, stupid, blind, deaf). 11. Children who do not have the above risk factors but are found to deviate from normal development during medical checkups. Parents of infants with the above risk factors should bring their babies to the Pediatric Neurology Department or Neurological Rehabilitation Department on a regular basis.